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Kambo rituals rub frog secretions into small burns, and Australia bans it

Kambo comes from the waxy skin secretion of the giant leaf frog, an Amazonian tree frog. In ceremonies, practitioners burn small spots on the arm or leg and dab the dried substance onto the wounds. Indigenous groups have long used it spiritually; Western detox fans adopted it more recently, despite no scientific evidence it treats anything.

The frog, Phyllomedusa bicolor, lives in the Amazon and Orinoco basins and goes by names such as giant monkey frog or blue-and-yellow frog. Its Portuguese nickname, sapo, simply means toad, and the practice is also called vacina do sapo, the frog vaccine. Collecting the secretion involves catching a frog and tying its limbs outstretched to four sticks. Stressed, it releases a peptide-rich defensive film from its skin, which is scraped off and dried before the animal is let go.

The tradition belongs to Panoan-speaking peoples of the south-eastern Amazon, including the Matsés, Marubo, Yawanawá and Kaxinawá; ethnographers have studied its role in Noke Kuin medicine in the Brazilian state of Acre. There it is a ritual with strong religious meaning, and in native practice the secretion is wiped off after 15 to 20 minutes. Researchers argue that Western accounts often ignore or belittle that spiritual context in favour of a purely biomedical frame, while commercialising the ceremony.

Kambo spread to Brazilian cities from the mid-twentieth century and reached the wider world as an alternative therapy in the late 2010s, usually sold as a cleanse in group sessions called kambo circles. Effects include a racing heart, low blood pressure, nausea and vomiting, driven by contracting smooth muscle. A review of 50 studies covering 11 cases of acute poisoning found rare but severe outcomes, among them psychosis, kidney and liver damage, seizures, a torn oesophagus and some deaths, though pre-existing medical conditions may have played a part.

Drinking large amounts of water during a session appears especially risky, linked with a hormone disorder called SIADH and dangerous drops in potassium, magnesium and phosphate. Hospital care focuses on protecting organs and restoring electrolytes, and naloxone is being studied as a possible antidote. Brazil banned selling and marketing kambo in 2004, Chile forbids importing it, and in 2021 Australia's Therapeutic Goods Administration listed it as a schedule 10 poison, the class considered too dangerous to sell or use.

Source: Kambo (drug)

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