How a pioneering 1954 surgery evolved into a life-saving medical standard today.

How does kidney transplant surgery work? - Alexander H. Toledo · 5:18 · Video: TED-Ed · Watch at the source

In short: Kidney transplants are now a routine procedure, but they began with a high-stakes experiment. This video explores the science behind matching donors to recipients and the surgical process that allows a transplanted kidney to function, transforming lives seventy years after the first successful attempt.

In 1954, Joseph Murray performed a groundbreaking kidney transplant between identical twins, proving the procedure could succeed. This initial success relied on the genetic match provided by the donor's twin status, which minimized the risk of rejection.

Today, the landscape of transplantation has expanded significantly. Nearly 100,000 kidney transplants are now performed annually in the United States. The procedure involves complex matching protocols to ensure compatibility between donors and recipients, allowing the transplanted organ to sustain the patient's health.

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