The surgeon who accidentally erased a man's ability to form memories

What happens when you remove the hippocampus? - Sam Kean · 5:26 · Video: TED-Ed · Watch at the source

In short: When a 1950s surgery intended to cure seizures resulted in the permanent loss of long-term memory, it provided a unique window into the human brain. This video explores the life of Henry Molaison and what his case revealed about our internal archives.

Following a skull fracture that caused seizures, patient Henry Molaison (H.M.) underwent surgery by Dr. William Skoville to remove his hippocampus. While the procedure successfully stopped the seizures, it resulted in a profound side effect: H.M. could no longer form new long-term memories.

H.M.'s case became a cornerstone of neuroscience, offering a rare opportunity to study the brain's memory mechanisms in a living human. His experience remains a primary source of understanding how the hippocampus functions as a gateway for converting short-term experiences into lasting records.

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