How does a single cell transform into a complex, functioning human being?

Where do I come from? - Alison Woollard's 2013 Christmas Lectures 1/3 · 59:10 · Video: The Royal Institution · Watch at the source

In short: Alison Woollard explores the mysteries of developmental biology, tracing the journey from a single cell to a fully formed organism. This lecture series examines how identical DNA produces diverse cell types and whether we can harness these biological processes to regenerate limbs or extend human life.

Every human body begins as a single cell, yet eventually comprises trillions of cells. A fundamental biological puzzle is how these cells, all carrying identical DNA, differentiate into specialized structures like heart, skin, blood, or brain cells. The lecture series investigates the mechanisms that dictate when and where these cells act, grow, and communicate.

Presented by Alison Woollard of the University of Oxford during the 2013 Christmas Lectures, the series looks at the broader implications of developmental biology. By studying how animals regenerate limbs and how stem cells specialize, researchers are beginning to uncover the secrets of life's formation. These insights raise profound questions about our relationship with other creatures and the potential consequences of manipulating the fundamental fabric of life.

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