The molecular hijacking of the human immune system by HIV

A-Level Biology - HIV - Structure | How it Replicates | How it Causes AIDS (2027/28 exams) · 5:43 · Video: Cognito · Watch at the source

In short: This video breaks down the biological mechanics of HIV, from its unique structural components to the complex replication cycle that compromises the human immune system.

The video explores how HIV utilizes specific components—including RNA genetic material, the reverse transcriptase enzyme, and attachment proteins—to infiltrate T helper cells. It details the replication cycle: the virus attaches to a host cell, injects its RNA, converts it into DNA via reverse transcription, and integrates that DNA into the host's own genome.

The content tracks the progression from transmission and acute infection through a latency period to the development of AIDS. It explains how this process weakens the immune system, making the body vulnerable to opportunistic infections, and briefly covers how Antiretroviral Therapy (ART) is used to manage the virus.

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