New computational tool tracks gene variations across diverse genomes
In short: Researchers have developed GENESPACE, a new computational framework designed to map gene positions and variations across multiple species. By integrating conserved gene order and orthology, the tool allows scientists to track changes in gene presence, copy number, and structural variations across different biological scales.
The researchers demonstrated the tool's utility by analyzing vertebrate sex chromosome evolution over 300 million years, the diversity of the grass family, and various maize cultivars. While powerful for complex genomes, the study focuses on the tool's implementation and demonstration across specific taxonomic groups.
Why it matters: This new tool provides a way to visualize how genes move and change across vast evolutionary timescales.
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Sources
- Source: Research: Lovell et al. (2022). GENESPACE tracks regions of interest and gene copy number variation across multiple genomes. eLife. · cc by
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