No one has found a natural English sentence using each letter exactly once
A pangram squeezes the whole alphabet into one sentence. The fox that jumps over a lazy dog has done that job since at least the late 19th century, testing Western Union's telex lines. The harder goal, every letter used just once, has only been reached in English with oddities like cwm and vext.
Pangrams earn their keep in practical ways. Printers and type designers use them to show off a font, typists and calligraphers drill with them, and engineers once used them to check that communication equipment passed every character correctly. Many computer programs still preview typefaces with the famous fox. Short examples are hard to write because they demand rare words, whereas longer ones leave room for jokes.
A perfect pangram is effectively an anagram of the alphabet. The best English attempts cheat a little with abbreviations or names, or else they lean on obscurities. One favourite, Cwm fjord-bank glyphs vext quiz, borrows cwm from Welsh for a bowl-shaped glacial hollow, spells vexed in an antique way and uses quiz in its old sense of an eccentric person. Decoded, it describes carvings at the edge of a sea inlet puzzling an oddball.
Other scripts make the trick easier. The Iroha is a celebrated perfect pangram of the Japanese syllabary, and the Hanacaraka does the same for Javanese script, where it also serves as the standard order for reciting the letters. Finnish has a tidy perfect example about a man named Albert buying a bassoon and blowing a wheezy tune on it, provided the letters reserved for foreign words are left out.
Languages that share the Latin alphabet but never use some of its letters face a choice: stick to native words or smuggle in loanwords. Whisky, a Gaelic borrowing found in many tongues, turns up constantly because it supplies k, w and y at once. Czech writers, meanwhile, prize a sentence about devils' saxophones blaring waltzes and quicksteps, which packs in every accented letter even though it misses some plain ones, and a Dutch example has a wise lynx admiring an aqueduct.
Source: Pangram