Metabolic syndrome review ties insulin resistance to diabetes and heart disease risk
In short: A review of research on metabolic syndrome—a cluster of conditions including insulin resistance, unhealthy blood fat levels, central obesity and high blood pressure—describes the condition as closely tied to chronic low-grade inflammation and insulin resistance. The authors note that, left unaddressed, the syndrome tends to raise the chances of developing diabetes and cardiovascular disease, which remains the world's leading cause of illness and death.
The review traces how both genetic and acquired factors feed into insulin resistance and inflammation, and summarizes current knowledge on the condition's history, biology and treatment approaches.
Because it draws together existing research rather than presenting new experiments, and because many aspects of the condition are still poorly understood, the picture offered here remains incomplete.
Why it matters: Understanding the inflammatory and metabolic roots of this syndrome could help address its role in diabetes and heart disease risk.
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