Why every single cell in your body is running on a 24-hour schedule

How does your body clock work? - with Aarti Jagannath · 57:14 · Video: The Royal Institution · Watch at the source

In short: Our bodies are tuned to a rhythmic world where day and night demand different biological states. Aarti Jagannath explains how our internal circadian clocks function, how they synchronize with our environment, and the consequences of living in a 24/7 society that often confuses our natural timing.

Every cell in the human body contains a circadian clock that governs our internal rhythm. This system is not static; it actively aligns itself with the outside world by processing time cues derived from both our physical environment and our daily behaviors. When these signals become contradictory—a common occurrence in modern, always-on lifestyles—the clock can fall out of sync.

Aarti Jagannath, an Associate Professor at the University of Oxford’s Nuffield Department of Clinical Neurosciences, explores the mechanisms behind these rhythms and the potential for clinical interventions when the system goes awry. Her work, which includes founding the company Circadian Therapeutics, bridges the gap between fundamental neuroscience and practical health applications.

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