How do we see the invisible architecture of crystals and their hidden molecular structures?

The Architecture of Crystals - John M. Thomas and David Phillips's 1987 Christmas Lectures 2/6 · 57:19 · Video: The Royal Institution · Watch at the source

In short: John Meurig Thomas explores the complex internal arrangements of crystals and proteins. By bombarding samples with light and electrons, he demonstrates how diffraction patterns allow scientists to map molecular positions and understand the fundamental link between a structure and its function.

Filmed at the Royal Institution on December 21, 1987, this lecture utilizes physical models, computer software, and live X-ray demonstrations to decode the architecture of materials. Thomas illustrates these concepts using Egyptian Blue, showing how diffraction analysis reveals the specific constituents of a pigment.

While crystals existed millions of years before life, their modern applications are transformative. From the first ruby-based laser created in the late 20th century to current roles in medicine, communications, and clean energy, crystals remain central to scientific progress. Professors John Meurig Thomas and David Phillips highlight how these structures serve as the foundation for both historical experiments and future technological innovation.

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