A unique gut microbiome pattern may signal healthy aging and longer life
In short: Researchers who analyzed the gut microbiomes of over 9,000 individuals found that as people age, their internal microbial communities become increasingly unique to them. This shift toward a distinct, individual-specific microbiome pattern is associated with healthy aging and can help predict survival rates in older adults.
The study identified that healthy aging is characterized by a decrease in common core bacteria, such as Bacteroides, and a corresponding increase in unique microbial metabolic outputs in the blood. In contrast, individuals who maintain a high dominance of these common bacteria into their 80s showed a lower likelihood of survival over a four-year period.
The researchers used data from three independent cohorts to observe these trends. However, because this was an observational study, it identifies associations rather than proving a direct cause-and-effect relationship between microbiome composition and longevity.
Why it matters: The way our gut bacteria change with age can serve as a biological marker for healthy aging and longevity.
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Sources
- Summary by Intellect · source: Research: Wilmanski et al. (2021). Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nature metabolism.
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