The prickly soursop is a tropical superfood, but its seeds are strictly off-limits.

The prickly soursop is a tropical superfood, but its seeds are strictly off-limits.
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In short: Known as guanabana or graviola, the soursop is a creamy, sweet-tart fruit native to South America. While it is packed with fiber and antioxidants, the plant hides a dangerous secret: its seeds are toxic, and concentrated extracts may pose serious neurological risks. Enjoy the fresh pulp, but avoid the supplements.

The soursop, or Annona muricata, is a broadleaf evergreen tree native to the tropical Americas. Its fruit is unmistakable, resembling an oversized, spiky avocado that can grow up to 35 centimeters long and weigh as much as 10 kilograms. Beneath the leathery, inedible skin lies a white, creamy pulp often compared to a blend of strawberry, apple, and pineapple. While it is a nutrient-dense addition to smoothies and sorbets, the plant is also the subject of intense, often overblown, health claims.

Traditional healers have long utilized various parts of the soursop plant, and modern lab studies have explored its potential antibacterial, anti-inflammatory, and blood-sugar-regulating properties. However, these findings are preliminary. While some research suggests soursop extracts might kill cancer cells in a laboratory setting, there have been no human studies to support these results. Experts warn that the public should not rely on soursop as a medical treatment, especially since the FDA does not regulate soursop teas or supplements.

The primary concern lies in the compound annonacin, which is found in the fruit, leaves, and seeds. Ingestion of large doses of soursop extracts has been linked to symptoms resembling Parkinson’s disease, including muscle rigidity, gait issues, and slowness of movement. Furthermore, these compounds can interfere with medications for diabetes and high blood pressure. While eating the fresh, raw fruit is generally considered safe, consumers are advised to discard the toxic black seeds and exercise caution regarding their total sugar intake, as a single fruit can contain up to 80 grams of sugar.

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